legalphilly.comThe worth of creating extensive, tissue-specific maps of protein lysine acetylation sites is further underscored by the numerous function of posttranslational modifications in the evolution and phenotypic composition of vertebrates, as indicated by the significant selective stress gene regulatory elements near posttranslational-modifying enzymes have come underneath in placental animals ( Lowe et al., 2011 ).

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Methylation of particular histone lysine residues serves as a submit-translational epigenetic modification that controls the expression of genes by serving as 'markers' for the recruitment of specific complexes that direct the organization of chromatin.

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