simpli.comThose included: lysine methylations on the C-terminus of the sequence or detected in peptides with acidic residues (doable artifacts of methyl esterification of the carboxylic group) and peptides with deamidation on the C-terminal arginine (tryptic cleavage after a deamidated residue have been just lately proven as a highly unlikely occasion 41 ). These figures are extremely significantly in favour of lysine aspirin nasal therapy: p = zero.019, zero.007, zero.004 respectively.

Among them we recognized histone H3 lysine 27 acetylation (H3K27Ac) as a modification upregulated in CRC