You enter the arena with exactly eight cards, and if those eight cards happen to be completely countered by the opponent's deck, you are in serious trouble.

It means abandoning your primary win condition and using your cards in bizarre, unintended ways just to survive.
The Unwinnable Fight
The first step in adapting is recognizing that your standard game plan is mathematically impossible to execute.

This often involves completely abandoning offense and focusing entirely on flawless defense, hoping to punish a massive mistake by the opponent or stall for a draw.
Use spells aggressively if your troops cannot connect.If they build an impenetrable fortress in the left lane, immediately start attacking the right lane to force them to spread their defenses.Accept that some games are just about survival. Creative Card Usage
If you are playing that Golem deck and the Golem is useless, perhaps your Night Witch or Baby Dragon can become your primary attackers.

This also applies to defense; if they have a massive push approaching and your primary defensive building is out of rotation, you must improvise.
SituationStandard Play (Fails)The SolutionOpponent has Inferno Tower, you have GolemPlay Golem, watch it melt instantly, lose 8 elixirUse Golem strictly on defense to block their attacks, and rely entirely on spells to damage their towerOpponent is using massive air swarm (Minion Horde)Try to defend with single-target Musketeer, fail instantlySacrifice your Ice Golem to kite them across the map until they die to Princess tower arrows The Mental Gymnastics
Never assume a match is over just because the opening hand was terrible.

Flexibility is the ultimate weapon.

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